Grant ANR PRC and PRME
24/07/2023 .Emmanuelle Bille was granted ANR PRME for her project on N. meningitidis and filamentous phage biology. The Neisseria group was also granted ANR PRC in collaboration with Sandrine Bourdoulous. …
Congratulation to Morgane Wuckelt and Elif UYAR
24/07/2023 .Morgane Wuckelt and Elif Uyar have been awarded a PhD Track Grant from BioSPC. We are all very proud and very excited about the science to come. Morgane will …
Engineered human microvasculature to study human infectious diseases
27/03/2023 . Implantation of engineered human microvasculature to study human infectious diseases in mouse models.Sophia Schönherr-Hellec et al iScience 2023 Animal models for studying human pathogens are crucially lacking. We …
Genomic analysis of S. aureus sequential isolates
27/03/2023 . Genomic analysis of Staphylococcus aureus sequential isolates from lungs of patients with cystic fibrosisDing et al Microbes and Infection 2023 Staphylococcus aureus is the predominant pathogen in children …
Grant ANR PRC – Anne Jamet
03/09/2022 .Anne Jamet was granted ANR PRC for her project on S. aureus, skin microbiota and host immune responses Deciphering how the interplay between dysbiosis and MAIT cells impacts skin …
Lung-Adapted Staphylococcus aureus Trigger a Proinflammatory Response
07/05/2022 . Lung-Adapted Staphylococcus aureus Isolates With Dysfunctional Agr System Trigger a Proinflammatory ResponseElodie Ramond et al The Journal of Infectious Diseases 2022 BackgroundStaphylococcus aureus dominates the lung microbiota of children …
Mechanical Activation of the β2-Adrenergic Receptor by Meningococci (Review)
02/05/2022 .Mechanical Activation of the β2-Adrenergic Receptor by Meningococcus: A Historical and Future Perspective Analysis of How a Bacterial Probe Can Reveal Signalling Pathways in Endothelial Cells, and a Unique …
The minor pilin PilV is necessary for meningococcal type IV pilus adhesion
12/11/2021 .The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus Jean-Philippe Barnier et al PNAS 2021 Neisseria meningitidis utilizes type IV pili (T4P) …
The pentose phosphate pathway in pathogenic Francisella
03/08/2021 .The pentose phosphate pathway constitutes a major metabolic hub in pathogenic FrancisellaHéloise Rytter et al PLOS Pathogens 2021. Metabolic pathways are now considered as intrinsic virulence attributes of pathogenic …
Grant ANR JCJC – Anne Jamet
03/08/2021 .Anne Jamet was granted ANR JCJC for her project on S. aureus and chronic lung infections in cystic fibrosis Impact of S. aureus on the outcome of chronic lung …
Congratulation to Audrey LAURENT, Clémence MOUVILLE and Xiali FU
02/08/2021 .Audrey LAURENT and Clémence MOUVILLE have been awarded a PhD Track Grant from BioSPC. Xiali FU has been awarded a PhD Track Grant from China Scholarship Council. We are …
MRSA Virulence in a new Drosophila Larval Model
23/06/2021 .Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the Drosophila Larval ModelElodie Ramond et al mBIO 2021 MRSA Virulence in a new Drosophila Larval ModelAntibiotic-resistant Staphylococcus …
Type IV pilus retraction enables sustained bacteremia
Le 19/02/2021 .Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model. Jean-Philippe Barnier et al PLOS …
High resolution typing of Staphylococcus epidermidis
28/12/2020 .High resolution typing of Staphylococcus epidermidis based on cgMLST to investigate the hospital spread of multidrug resistant clones. Jamet et al J Clin Microbiol 2020 Dec 16 News linked to Anne …
Grant « Sauver la Vie » – Anne Jamet
13/04/2020 .Anne Jamet received the « Sauver la Vie » grant from Université Paris Descartes
Type IV Pili recognize a Complex N-glycan
Receptor Recognition by Meningococcal Type IV Pili Relies on a Specific Complex N-glycan. Leguennec et al Proc Natl Acad Sci U S A, 117 (5), 2606-2612 2020 Feb 4 News linked to Mathieu …
A Sheath Phosphorylation control T6SS Assembly
Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System. Ziveri et al, Mol Cell Proteomics, 2019 Dec;18(12):2418-2432 News linked to …
Sialic Acid Mediates β2AR activation by type IV pili
Sialic Acid Mediated Mechanical Activation of β 2 Adrenergic Receptors by Bacterial Pili. Virion et al, Nat Commun, 10 (1), 4752 2019 Oct 18 News linked to Mathieu Coureuil & Xavier Nassif …
Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence
Chronic Staphylococcus Aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence. Tan et al, Clin Infect Dis, 69 (11), 1937-1945 2019 Nov 13 News …