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New Publication / Team N. meningitidis

Engineered human microvasculature to study human infectious diseases

27/03/2023 . Implantation of engineered human microvasculature to study human infectious diseases in mouse models.Sophia Schönherr-Hellec et al iScience 2023 Animal models for studying human pathogens are crucially lacking. We …

New Publication / Team S. aureus

Genomic analysis of S. aureus sequential isolates

27/03/2023 . Genomic analysis of Staphylococcus aureus sequential isolates from lungs of patients with cystic fibrosisDing et al Microbes and Infection 2023 Staphylococcus aureus is the predominant pathogen in children …

Anne Jamet / Award & Grant

Grant ANR JCJC – Anne Jamet

03/09/2022 .Anne Jamet was granted ANR PRC for her project on S. aureus, skin microbiota and host immune responses Deciphering how the interplay between dysbiosis and MAIT cells impacts skin …

New Publication / Team S. aureus

Lung-Adapted Staphylococcus aureus Trigger a Proinflammatory Response

07/05/2022 . Lung-Adapted Staphylococcus aureus Isolates With Dysfunctional Agr System Trigger a Proinflammatory ResponseElodie Ramond et al The Journal of Infectious Diseases 2022 BackgroundStaphylococcus aureus dominates the lung microbiota of children …

New Publication / Team N. meningitidis

Mechanical Activation of the β2-Adrenergic Receptor by Meningococci (Review)

02/05/2022 .Mechanical Activation of the β2-Adrenergic Receptor by Meningococcus: A Historical and Future Perspective Analysis of How a Bacterial Probe Can Reveal Signalling Pathways in Endothelial Cells, and a Unique …

New Publication / Team N. meningitidis

The minor pilin PilV is necessary for meningococcal type IV pilus adhesion

12/11/2021 .The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus Jean-Philippe Barnier et al PNAS 2021 Neisseria meningitidis utilizes type IV pili (T4P) …

New Publication / Team S. aureus

The pentose phosphate pathway in pathogenic Francisella

03/08/2021 .The pentose phosphate pathway constitutes a major metabolic hub in pathogenic FrancisellaHéloise Rytter et al PLOS Pathogens 2021. Metabolic pathways are now considered as intrinsic virulence attributes of pathogenic …

Anne Jamet / Award & Grant

Grant ANR JCJC – Anne Jamet

03/08/2021 .Anne Jamet was granted ANR JCJC for her project on S. aureus and chronic lung infections in cystic fibrosis Impact of S. aureus on the outcome of chronic lung …

Award & Grant / Team N. meningitidis / Team S. aureus

Congratulation to Audrey LAURENT, Clémence MOUVILLE and Xiali FU

02/08/2021 .Audrey LAURENT and Clémence MOUVILLE have been awarded a PhD Track Grant from BioSPC. Xiali FU has been awarded a PhD Track Grant from China Scholarship Council. We are …

Ramond et al mBIO 2021
New Publication / Team S. aureus

MRSA Virulence in a new Drosophila Larval Model

23/06/2021 .Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the Drosophila Larval ModelElodie Ramond et al mBIO 2021 MRSA Virulence in a new Drosophila Larval ModelAntibiotic-resistant Staphylococcus …

PLOS Pathogen Barnier et al 2021
New Publication / Team N. meningitidis

Type IV pilus retraction enables sustained bacteremia

Le 19/02/2021 .Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model. Jean-Philippe Barnier et al PLOS …

JClinMicro_AJ2021
New Publication / Team S. aureus

High resolution typing of Staphylococcus epidermidis

28/12/2020 .High resolution typing of Staphylococcus epidermidis based on cgMLST to investigate the hospital spread of multidrug resistant clones. Jamet et al J Clin Microbiol 2020 Dec 16 News linked to Anne …

Anne Jamet / Award & Grant

Grant « Sauver la Vie » – Anne Jamet

13/04/2020 .Anne Jamet received the « Sauver la Vie » grant from Université Paris Descartes

New Publication / Team N. meningitidis

Type IV Pili recognize a Complex N-glycan

Receptor Recognition by Meningococcal Type IV Pili Relies on a Specific Complex N-glycan. Leguennec et al Proc Natl Acad Sci U S A, 117 (5), 2606-2612 2020 Feb 4 News linked to Mathieu …

New Publication / Team F. tularensis

A Sheath Phosphorylation control T6SS Assembly

Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System. Ziveri et al, Mol Cell Proteomics, 2019 Dec;18(12):2418-2432 News linked to …

New Publication / Team N. meningitidis

Sialic Acid Mediates β2AR activation by type IV pili

Sialic Acid Mediated Mechanical Activation of β 2 Adrenergic Receptors by Bacterial Pili. Virion et al, Nat Commun, 10 (1), 4752 2019 Oct 18 News linked to Mathieu Coureuil & Xavier Nassif …

New Publication / Team S. aureus

Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence

Chronic Staphylococcus Aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence. Tan et al, Clin Infect Dis, 69 (11), 1937-1945 2019 Nov 13 News …

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